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Leukaemia Biology Program

Program Head: Associate Professor Richard Lock (biography)

RESEARCH AREAS
Drug resistance in childhood leukaemia
Pre-clinical evaluation of new therapies
Biology of childhood leukaemia
New therapies for AML

Leukaemias account for approximately one third of all paediatric malignancies and cause the greatest number of cancer-related deaths in children. The long-term goal of the Leukaemia Biology Program is to improve the treatment of children with leukaemia through the development of new therapies and their preclinical testing in clinically relevant experimental models.

STUDENT PROJECTS

  • Mechanisms of glucocorticoid resistance in acute lymphoblastic leukaemia
  • Phosphotyrosine profiling in acute lymphoblastic leukaemia
  • Characterisation of stem cells in paediatric leukaemia
  • Modelling minimal residual disease in acute lymphoblastic leukaemia
  • New treatments for acute lymphoblastic leukaemia
Associate Professor Richard Lock